Searchable abstracts of presentations at key conferences in endocrinology

ea0090p262 | Late-Breaking | ECE2023

Define cell-type-specific disease signatures regulating white adipose tissue of women with polycystic ovary syndrome

Li Congru , Eriksson Gustaw , Lu Haojiang , Vannay Alana , Lindgren Eva , Hirschberg Linden Angelica , Deng Qiaolin , Stener-Victorin Elisabet

White adipose tissue (WAT) is a dynamic and heterogeneous organ composed of different cell types involved in a wide array of biological processes. We know that women with polycystic ovary syndrome (PCOS) suffer from insulin resistance and type 2 diabetes which is associated with pathological white adipose tissue (WAT) function and expansion characterized by hypertrophic adipocytes, altered production and release of lipids and adipokines, and chronic low-grade tissue inflammati...